PROTON PUMP INHIBITORS ESOMEPRAZOLE- Nexium Delayed-Release Capsules, Nexium for Delayed-Release Oral Suspension
LANSOPRAZOLE- Prevacid, Prevacid NapraPAC, Prevacid Solutab
PANTOPRAZOLE- Pantoloc, Protonix RABEPRAZOLE- Aciphex
OMEPRAZOLE- Losec, Prilosec, Prilosec OTC, Rapinex Powder for Oral Suspension, Zegerid Capsules, Zegerid Chewable Tablets, Zegerid Powder

Habit forming? No
Prescription needed? Yes
Available as generic? Yes, for some
Drug class: Antiulcer agent; proton pump inhibitor

Treats gastro esophageal reflux (splashing of stomach acid from the stomach up onto the lower end of the esophagus).

- Treats ulcers in the stomach and duodenum.

- Treats any disorder associated with excess production of stomach acid (such as Zollinger-Ellison syndrome).

How to take Protonix:

- Delayed-release and extended-release Protonix capsule: Swallow whole with liquid. Do not crush, chew or break open.

- Delayed-release oral suspension: Follow instructions on prescription.

- Immediate - release capsule: Swallow Protonix whole with water (not other liquids). Do not crush Protonix, chew or break open.

- Protonix Powder: Follow instructions on prescription.

- Protonix Tablet (enteric coated): Swallow whole with liquid. Do not crush, crumble or chew Protonix tablets.

When to take PROTONIX:

- Once daily, immediately before a meal (preferably breakfast), unless otherwise directed by your doctor.

- With once-a-day dosing, it is important to take the medicine on schedule.

If you forget a PROTONIX dose:

- Take as soon as you remember. If it is almost time for the next dose, wait for next scheduled dose (don't double this dose).

What PROTONIX does:

- Stops the production of stomach acid.

Time lapse before drug works:

- Thirty minutes to 3 hours.

Don't take with:

- Any other medicine or any dietary supplement without consulting your doctor or pharmacist.

SYMPTOMS: Severe drowsiness, seizures, breathing difficulty, decreased body temperature.


None expected.

Common PROTONIX Side Effects:

Diarrhea, stomach pain.

Infrequent PROTONIX Side Effects:

Nausea, loss of appetite, headache, heartburn, muscle pain, skin rash, drowsiness.

Rare PROTONIX Side Effects:

Weakness or unusual tiredness, sore throat and fever, sores on mouth, unusual bleeding or bruising, cloudy or bloody urine, urination changes (difficult, frequent or painful).

Don't take PROTONIX if:

- You are allergic to proton pump inhibitors.

Before you start PROTONIX, consult your doctor If:

- You are allergic to any medicines, foods or other substances.

- You have or have had liver disease.

- You have a stomach infection.

Over age 60:

- No special problems expected.


- Risk factors may vary for drugs in this group.


- It is unknown if drug passes into milk. Avoid or discontinue nursing until you finish medicine.

- Consult doctor for advice on maintaining milk supply.

Infants & children:

- Lansoprazole is used in children ages 1 to 17 years.

- Esomeprazole is used in children ages 12 to 17 for the short-term treatment of gastro esophageal reflux disease.

- For other drugs in this group, consult doctor before using in children.

Prolonged PROTONIX use:

- The length of treatment can run from 4 to 8 weeks or may be indefinite. Though your symptoms may improve in 1 to 2 weeks, your doctor will determine when healing is complete.

Skin & sunlight:

- No special problems expected.

Driving, piloting or hazardous work:

- No special problems expected.

Discontinuing PROTONIX:

- Don't discontinue without consulting doctor until you complete prescribed dose, even though symptoms diminish or disappear


- Advise any doctor or dentist whom you consult that you take this medicine.

- If directed by your doctor, it is permissible and sometimes helpful to take with antacids to relieve upper abdominal pain. Antacids may be used more than once daily if needed.

- The brand name Zegerid contains sodium bicarbonate (a form of salt). If you are on a diet that restricts salt or sodium, consult your doctor before using this drug.

- May affect results of some medical tests.

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