Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins Terms and Definitions




Carrier Proteins

Medical Definition: Transport proteins that carry specific substances in the blood or across cell membranes.
Guide Notes: do not confuse BINDING PROTEINS (X ref) with PROTEIN BINDING; do not use CARRIER PROTEINS if the protein functions as a receptor: use instead the pertinent RECEPTORS term; not for antigenic carriers ( = ANTIGENS)
Also Called: Binding Protein
Previously Indexed: Protein Binding (1966-1970),Proteins (1966-1970)
Carrier Proteins Categories.
Canadian Medical Guide Definition Acyl Carrier Protein - Consists of a polypeptide chain and 4'-phosphopantetheine linked to a serine residue by a phosphodiester bond. Acyl groups are bound as thiol esters to the pantothenyl group. Acyl carrier protein is involved in every step of fatty acid synthesis by the cytoplasmic system.
Canadian Medical Guide Definition Androgen-Binding Protein - Carrier proteins produced in the Sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. They participate in the transport of androgens. Androgen-binding protein has the same amino acid sequence as SEX HORMONE BINDING-GLOBULIN. They differ by their sites of synthesis and post-translational oligosacaccharide modifications.
Canadian Medical Guide Definition Calcium-Binding Proteins - Proteins to which calcium ions are bound. They can act as transport proteins, regulator proteins, or activator proteins. They typically contain EF HAND MOTIFS.
Canadian Medical Guide Definition Calmodulin-Binding Proteins - Proteins which bind calmodulin. They are found in many tissues and have a variety of functions including F-actin cross-linking properties, inhibition of cyclic nucleotide phosphodiesterase and calcium and magnesium ATPases.
Canadian Medical Guide Definition F-Box Proteins - A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. They play an important role in process of protein ubiquition by associating with a variety of substrates and then associating into SCF UBIQUITIN LIGASE complexes. They are held in the ubiquitin-ligase complex via binding to SKP DOMAIN PROTEINS.
Canadian Medical Guide Definition Follistatin - A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37 kD and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.
Canadian Medical Guide Definition Follistatin-Related Proteins - Broadly distributed glycoproteins that are homologous to the activin-binding protein, FOLLISTATIN. These follistatin-related proteins are encoded by a number of genes.
Canadian Medical Guide Definition Insulin-Like Growth-Factor-Binding Proteins - A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. (Int J Gynaecol Obstet 1992;39(1):3-9)
Canadian Medical Guide Definition Iron-Binding Proteins - Proteins that specifically bind to IRON.
Canadian Medical Guide Definition Membrane Transport Proteins - Membrane proteins whose primary function is to facilitate the transport of molecules across a biological membrane. Included in this broad category are proteins involved in active transport (BIOLIOGICAL TRANSPORT, ACTIVE), facilitated transport and ION CHANNELS.
Canadian Medical Guide Definition Phosphate-Binding Proteins - Proteins that bind to and are involved in the metabolism of phosphate ions.
Canadian Medical Guide Definition RNA-Binding Proteins - Proteins that bind to RNA molecules. Included here are RIBONUCLEOPROTEINS and other proteins whose function is to bind specifically to RNA.
Canadian Medical Guide Definition S-Phase Kinase-Associated Proteins - A family of structurally-related proteins that were orginally identified by their ability to complex with cyclin proteins (CYCLINS). They share a common domain that binds specifically to F-BOX MOTIFS. They take part in SKP CULLIN F-BOX PROTEIN LIGASES, where they can bind to a variety of F-BOX PROTEINS.
Canadian Medical Guide Definition Transferrin-Binding Proteins - A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize transferrin-binding proteins to acquire their supply of iron from serum.
Canadian Medical Guide Definition Vitamin D-Binding Protein - An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in the liver and carries vitamin D and its metabolites through the circulation and mediates the response of tissue. It is also known as group-specific component (Gc). Gc subtypes are used to determine specific phenotypes and gene frequencies. These data are employed in the classification of population groups, paternity investigations, and in forensic medicine.

Carrier Proteins Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

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