Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Insulin-Like Growth-Factor-Binding Proteins Terms and Definitions




Insulin-Like Growth-Factor-Binding Proteins

Medical Definition: A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. (Int J Gynaecol Obstet 1992;39(1):3-9)
Guide Notes: GEN or unspecified; prefer specifics; /biosyn /drug eff /physiol /ultrastruct permitted; DF: note short X refs
Previously Indexed: Carrier Proteins (1980-1995)
Insulin-Like Growth-Factor-Binding Proteins Categories.
Canadian Medical Guide Definition Insulin Like Growth-Factor-Binding Protein 4 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
Canadian Medical Guide Definition Insulin-Like Growth Factor Binding Protein 3 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
Canadian Medical Guide Definition Insulin-Like Growth Factor-Binding Protein 2 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
Canadian Medical Guide Definition Insulin-Like Growth-Factor Binding Protein 1 - One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
Canadian Medical Guide Definition Insulin-Like Growth-Factor-Binding-Protein 5 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
Canadian Medical Guide Definition Insulin-Like-Growth-Factor-Binding Protein 6 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.

Insulin-Like Growth-Factor-Binding Proteins Medical Definitions and Terms

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