Canadian Medical Guide > Vitamins & Mineral Food Supplement Guide

Vitamin B12 (Cyanocobalamin)

Vitamin / Mineral Supplement Overview:
Vitamin B-12, otherwise known as cyanocobalamin, performs as a coenzyme for the creation of DNA material. It also promotes growth and cell development and is important to fat, carbohydrate, and protein metabolism. Although vitamin B-12 is not found in plant foods, good sources of this supplement include meats, fish, eggs, and dairy products.

How Vitamin B12 (Cyanocobalamin) Works in the Body:
Growth and development of nerve, skin, hair, and blood cells
Vitamin B12 (Cyanocobalamin) produces genetic material
Metabolizes amino and fatty acids
Vitamin B12 (Cyanocobalamin) works to release food energy
Helps treat Alzheimer's disease
May help sufferers of nervous disorders
Vitamin B12 (Cyanocobalamin) could improve immune system
May see increase in energy and memory

The Following May Benefit from Vitamin B12 (Cyanocobalamin) Supplements:
Those with increased nutritional needs
Substance abusers
Those with chronic illnesses or recently undergone surgery, especially removal of portions of gastrointestinal tract
Burn and recently injured patients
Those with malignancies of the pancreas or bowels

Foods High in Vitamin B12 (Cyanocobalamin):
Beef liver
Blue cheese
Dairy products
Swiss cheese

Using Vitamin B12 (Cyanocobalamin):
Available as:
Liquid: the best form due to its high bioavailability and fast absorption. Always choose liquid as your first choice when supplementing your diet.

Tablets: available

Recommended Daily Vitamin B12 (Cyanocobalamin) Intakes
Men: 2.4 mcg
Women: 2.4 mcg
Pregnancy: 2.6 mcg
Lactation: 2.8 mcg

Medical Precautions: Consult your doctor if you have:

Over 55:
Those with achiorhydria may absorb less.

Keep doses within DRI.

Keep doses within DRI.

Vitamin B12 (Cyanocobalamin) Supplement Storage:
Heat and/or moisture may alter the vitamin. Refrigeration is recommended.

Symptoms of Deficiency:
Symptoms include nausea, loss of appetite, sore mouth, Diarrhoea, abnormal gait, loss of sensation in hands and feet, confusion, memory loss, and depression. Harmful anemia may be a result of this deficiency.

Vitamin B12 (Cyanocobalamin) Overdose:
Signs of Overdose:
When taken in conjunction with large doses of vitamin C, nosebleeds, ear bleeding, or dry mouth may occur.

Vitamin B12 (Cyanocobalamin) Side Effects:
Reaction or effect : What to do
Diarrhoea : Stop use and call doctor.
Skin itching : Obtain emergency treatment immediately

Interacts with : Combined effect
Tobacco/Alcohol : Reduces the absorption of vitamin.
Antibiotics : False low test results for vitamin may result.
Chloramphenicol : If vitamin is being used to treat anemia, response may be hindered.
Cholestyramine : Reduces the absorption of vitamin.
Colchicine : Reduces the absorption of Vitamin B12.
Epoetin : Reduces the absorption of Vitamin B12.
Folic acid : Vitamin deficiency masked in large doses.
Neomycin (oral forms) : Reduces the absorption of Vitamin B12.
Potassium (extended-release forms) : Reduces the absorption of vitamin.


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