| Medical Definition: |
A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol. |
| Guide Notes: |
a post-translational protein change |
| Also Called: |
Prenylation,Protein Farnesylation,Protein Geranylgeranylation,Protein Polyisoprenylation,Farnesylation,Geranylgeranylation,Isoprenylation |
| Previously Indexed: |
Protein Processing, Post-Translational (1987-1992) |
CANADIAN
MEDICAL GUIDE