Canadian Medical Guide > Chemicals and Drugs > Neurotransmitters and Neurotransmitter Agents > Neurotransmitter Agents Terms and Definitions




Neurotransmitter Agents

Medical Definition: Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
Guide Notes: GEN; prefer specifics; used for mapping supplementary chemicals; consider also SYNAPTIC TRANSMISSION /drug eff
Neurotransmitter Agents Categories.
Canadian Medical Guide Definition Adrenergic Agents - Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.
Canadian Medical Guide Definition Cholinergic Agents - Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage.
Canadian Medical Guide Definition Dopamine Agents - Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
Canadian Medical Guide Definition Excitatory Amino Acid Agents - Drugs used for their actions on any aspect of excitatory amino acid neurotransmitter systems. Included are drugs that act on excitatory amino acid receptors, affect the life cycle of excitatory amino acid transmitters, or affect the survival of neurons using excitatory amino acids.
Canadian Medical Guide Definition GABA Agents - Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
Canadian Medical Guide Definition Glycine Agents - Substances used for their pharmacological actions on glycinergic systems. Glycinergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
Canadian Medical Guide Definition Histamine Agents - Drugs used for their actions on histaminergic systems. Included are drugs that act at histamine receptors, affect the life cycle of histamine, or affect the state of histaminergic cells.
Canadian Medical Guide Definition Neurotransmitter Uptake Inhibitors - Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects.
Canadian Medical Guide Definition Serotonin Agents - Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.

Neurotransmitter Agents Medical Definitions and Terms

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