Canadian Medical Guide > Biological Sciences > Genetic Processes > Mutagenesis > DNA Repeat Expansion Terms and Definitions
DNA Repeat Expansion
Medical Definition: | An increase number of repeats of a genomic, tandemly repeated DNA sequence from one generation to the next. |
Also Called: | Expanded DNA Repeats |
Previously Indexed: | Repetitive Sequences, Nucleic Acid or specifics (1993-2003) |
Trinucleotide Repeat Expansion - An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs. |
DNA Repeat Expansion Medical Definitions and Terms
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