Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Lymphoma > Lymphoma, Non-Hodgkin > Lymphoma, Follicular Terms and Definitions




Lymphoma, Follicular

Medical Definition: Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centers of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-lymphocytes. This class of lymphoma usually occurs in older persons, is commonly multinodal, and possibly extranodal. Patients whose lymphomas present a follicular or nodular pattern generally have a more indolent course than those presenting with a diffuse pattern.
Guide Notes: a non-Hodgkin's lymphoma; DF: LYMPHOMA FOLLIC
Lymphoma, Follicular Categories.
Canadian Medical Guide Definition Lymphoma, Large-Cell, Follicular - Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular center cells retain their ability to form follicles varies with the state of B-cell transformation.
Canadian Medical Guide Definition Lymphoma, Mixed-Cell, Follicular - A low-grade malignant lymphoma of follicular pattern in which there is no clear preponderance of one cell type (small or large) over another. The large cells, cleaved or noncleaved, are often 2-3 times larger in diameter than normal lymphocytes.
Canadian Medical Guide Definition Lymphoma, Small Cleaved-Cell, Follicular - A low-grade malignant lymphoma of predominantly follicular pattern. Follicles are of relatively uniform size and shape and the cells are usually somewhat larger than normal lymphocytes. Nuclei are irregular with prominent indentations and cytoplasm can rarely be identified. Cells exhibiting these characteristics are often called centrocytes.

Lymphoma, Follicular Medical Definitions and Terms

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