Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Lymphoma > Lymphoma, Non-Hodgkin Terms and Definitions




Lymphoma, Non-Hodgkin

Medical Definition: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
Guide Notes: GEN & unspecified only: prefer specifics
Previously Indexed: Lymphoma (1966-1986)
Lymphoma, Non-Hodgkin Categories.
Canadian Medical Guide Definition Lymphoma, B-Cell - A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes.
Canadian Medical Guide Definition Lymphoma, Diffuse - Malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organized pattern. Patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern.
Canadian Medical Guide Definition Lymphoma, Follicular - Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centers of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-lymphocytes. This class of lymphoma usually occurs in older persons, is commonly multinodal, and possibly extranodal. Patients whose lymphomas present a follicular or nodular pattern generally have a more indolent course than those presenting with a diffuse pattern.
Canadian Medical Guide Definition Lymphoma, High-Grade - One of the three major prognostic groupings for non-Hodgkin lymphomas as proposed in the Working Formulation of the Non-Hodgkin's Lymphoma Pathologic Classification Project sponsored by the National Cancer Institute (1981). Lymphomas falling within this group have a relatively unfavorable survival potential.
Canadian Medical Guide Definition Lymphoma, Intermediate-Grade - One of the three major prognostic groupings for non-Hodgkin lymphomas as proposed in the Working Formulation of the Non-Hodgkin's Lymphoma Pathologic Classification Project sponsored by the National Cancer Institute (1981). Lymphomas falling within this group have an intermediate survival potential.
Canadian Medical Guide Definition Lymphoma, Low-Grade - One of the three major prognostic groupings for non-Hodgkin lymphomas as proposed in the Working Formulation of the Non-Hodgkin's Lymphoma Pathologic Classification Project sponsored by the National Cancer Institute (1981). Lymphomas falling within this group have a relatively favorable survival potential.
Canadian Medical Guide Definition Lymphoma, Mixed-Cell - Malignant lymphoma characterized by the presence of a mixed population of cells, with the smaller cells resembling lymphocytes and the larger ones histiocytes. It usually presents in a nodular (follicular) pattern, but may evolve into a diffuse pattern. (Dorland, 27th ed)
Canadian Medical Guide Definition Lymphoma, T-Cell - A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes.
Canadian Medical Guide Definition Lymphoma, Undifferentiated - A form of lymphoma in which relatively large stem cells with large nuclei, pale, scanty cytoplasm, and indistinct borders are predominant. The cells are undifferentiated, i.e., show no morphologic evidence of maturation toward lymphocytes or histiocytes.

Lymphoma, Non-Hodgkin Medical Definitions and Terms

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