Canadian Medical Guide > Diseases > Hemic and Lymphatic Diseases > Hematologic Diseases > Leukocyte Disorders > Phagocyte Bactericidal Dysfunction Terms and Definitions




Phagocyte Bactericidal Dysfunction

Medical Definition: Disorders in which phagocytic cells cannot kill ingested bacteria; characterized by frequent recurring infection with formulation of granulomas.
Guide Notes: immunodefic syndrome where phagocytes cannot kill bacteria
Previously Indexed: Granuloma (1966-1971),Immunologic Deficiency Syndromes (1968-1971),Phagocytosis (1966-1971)
Phagocyte Bactericidal Dysfunction Categories.
Canadian Medical Guide Definition Chediak-Higashi Syndrome - A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.
Canadian Medical Guide Definition Granulomatous Disease, Chronic - A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.
Canadian Medical Guide Definition Job's Syndrome - A disorder of neutrophils characterized by the presence of abnormal or absent chemotactic responses and hyperimmunoglobulinemia E. It is transmitted as an autosomal recessive trait and most cases reported have been in girls.

Phagocyte Bactericidal Dysfunction Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

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