Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines Terms and Definitions
Pyridines
Medical Definition: | |
Guide Notes: | pyridine nucleotides will probably be NAD or NADP |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease. | |
2,2'-Dipyridyl - A reagent used for the determination of iron. | |
Betahistine - A histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in Meniere's disease and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. | |
Carbolines - A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles. | |
Clopidol - A very effective anticoccidial agent used in poultry. | |
Dihydropyridines - Pyridine moieties which are partially saturated by the addition of two hydrogen atoms in any position. | |
Dimethindene - A histamine H1 antagonist. It is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies. | |
Disopyramide - A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties. | |
Doxylamine - Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM. | |
Indinavir - A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. | |
Metyrapone - An inhibitor of the enzyme STEROID 11 BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME. | |
Naphthylvinylpyridine - 4(1-Naphthylvinyl)pyridine hydrochloride. Cholinesterase inhibitor. Synonym: YuB 25. | |
Nevirapine - A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV infection and AIDS. | |
Pheniramine - One of the HISTAMINE H1 ANTAGONISTS with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus. | |
Picolines - A group of compounds that are monomethyl derivatives of pyridines. (From Dorland, 28th ed) | |
Pyridinium Compounds | |
Pyridones - Pyridine derivatives with one or more keto groups on the ring. | |
Pyrithioxin - A neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity. | |
Quinolinic Acids | |
Triprolidine - Histamine H1 antagonist used in ALLERGIC RHINITIS, ASTHMA, and URTICARIA. It is a component of COUGH and COLD medicines. It may cause drowsiness. | |
Tropicamide - One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic. |
Pyridines Medical Definitions and Terms
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