Canadian Medical Guide > Biological Sciences > Genetic Processes > Gene Expression Regulation > RNA Processing, Post-Transcriptional Terms and Definitions




RNA Processing, Post-Transcriptional

Medical Definition: Post-transcriptional biological modification of messenger, transfer, or ribosomal RNAs or their precursors. It includes cleavage, methylation, thiolation, isopentenylation, pseudouridine formation, conformational changes, and association with ribosomal protein.
Guide Notes: coord IM with specific RNA /metab (IM); DF: RNA PROC POST TRANSCRIPTIONAL
Previously Indexed: Nucleic Acid Precursors (1975-1982),RNA, Messenger (1966-1982),Transcription, Genetic (1973-1982)
RNA Processing, Post-Transcriptional Categories.
Canadian Medical Guide Definition RNA 3' End Processing - The steps that generate the 3' ends of mature RNA molecules. For most mRNAs (RNA, MESSENGER), 3' end processing referred to as POLYADENYLATION includes the addition of POLY A.
Canadian Medical Guide Definition RNA Editing - A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE).
Canadian Medical Guide Definition RNA Splicing - The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm.

RNA Processing, Post-Transcriptional Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

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