Canadian Medical Guide > Diseases > Disorders of Environmental Origin > Poisoning > Drug Toxicity > Serotonin Syndrome Terms and Definitions




Serotonin Syndrome

Medical Definition: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
Previously Indexed: Serotonin (1980-1992),Serotonin Uptake Inhibitors/adverse effects (1993-1998)

Serotonin Syndrome Medical Definitions and Terms

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