Canadian Medical Guide > Diseases > Disorders of Environmental Origin Terms and Definitions

Disorders of Environmental Origin

Medical Definition:	Disorders representing collectively the results of assault by external forces, rather than by organic or physiologic dysfunction or by pathogens.
Guide Notes:	not used for indexing CATALOG: do not use

Disorders of Environmental Origin Categories.

	DNA Damage - Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.
	Motion Sickness - Disorder caused by motion, as sea sickness, train sickness, car sickness, air sickness, or SPACE MOTION SICKNESS. It may include nausea, vomiting and dizziness.
	Occupational Diseases - Diseases due to factors involved in one's employment. (From Dorland, 28th ed)
	Poisoning - A condition or physical state produced by the ingestion, injection or inhalation of, or exposure to a deleterious agent.
	Substance-Related Disorders - Disorders related to substance abuse, the side effects of a medication, toxin exposure, and ALCOHOL-RELATED DISORDERS.
	Wounds and Injuries - Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.

Disorders of Environmental Origin Medical Definitions and Terms

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