Canadian Medical Guide > Anatomy > Digestive System > Gastrointestinal Tract > Upper Gastrointestinal Tract > Stomach > Gastric Mucosa Terms and Definitions

Gastric Mucosa

Medical Definition:	Surface epithelium in the stomach that invaginates into the lamina propria, forming gastric pits. Tubular glands, characteristic of each region of the stomach (cardiac, gastric, and pyloric), empty into the gastric pits. The gastric mucosa is made up of several different kinds of cells.
Guide Notes:	/secret permitted but consider GASTRIC JUICE /secret if pertinent, but not STOMACH /secret; mucosal neopl: coord NIM with STOMACH NEOPLASMS (IM) + histol type of neopl (IM); mucosal prolapse = GASTRIC MUCOSA (IM) + STOMACH DISEASES (NIM) + PROLAPSE (NIM)
Also Called:	Gastric Glands,Pyloric Glands,Cardiac Glands

Gastric Mucosa Categories.

	Chief Cells, Gastric - Epithelial cells that line the basal half of the gastric glands. Chief cells synthesize and secrete pepsinogen, a precursor of the enzyme pepsin.
	D Cells - Cells found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin.
	Enterochromaffin Cells - Group of basal granular cells of the gut whose granules stain readily with silver and chromium salts. The cells secrete serotonin, substance P, and enkephalins. There are three types: gastric (antral mucosa), duodenal, and intestinal.
	G Cells - Endocrine cells found in the pyloric gland mucosa (antral mucosa) of the stomach and responsible for the secretion of gastrin.
	Parietal Cells, Gastric - Cells of the gastric glands which secrete hydrochloric acid and intrinsic factor.

Gastric Mucosa Medical Definitions and Terms

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