Canadian Medical Guide > Chemicals and Drugs > Polycyclic Hydrocarbons > Steroids > Pregnanes Terms and Definitions

Pregnanes

Medical Definition:	Saturated derivatives of the steroid pregnane. The 5-beta series includes PROGESTERONE and related hormones; the 5-alpha series includes forms generally excreted in the urine.
Guide Notes:	do not confuse with PREGNENES

Pregnanes Categories.

	Pregnadienes - Pregnane derivatives containing two double bonds anywhere within the ring structures.
	Pregnanediol - An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.
	Pregnanediones - Pregnane derivatives in which two side-chain methyl groups or two methylene groups in the ring skeleton (or a combination thereof) have been oxidized to keto groups.
	Pregnanetriol - A metabolite of 17-ALPHA-HYDROXYPROTESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE.
	Pregnanolone - A pregnane found in the urine of pregnant women and sows. It has anesthetic, hypnotic, and sedative properties.
	Pregnatrienes - Pregnane derivatives containing three double bonds in the ring structures.
	Pregnenes - Unsaturated derivatives of PREGNANES.
	Tetrahydrocortisol

Pregnanes Medical Definitions and Terms

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