Canadian Medical Guide > Chemicals and Drugs > Polycyclic Hydrocarbons > Steroids > Pregnanes > Pregnadienes Terms and Definitions

Pregnadienes

Medical Definition:	Pregnane derivatives containing two double bonds anywhere within the ring structures.
Previously Indexed:	Pregnanes (1966-1972)

Pregnadienes Categories.

	Canrenoate Potassium - A synthetic pregnadiene derivative with anti-aldosterone activity.
	Canrenone - A synthetic pregnadiene compound with anti-aldosterone activity.
	Chlormadinone Acetate - An orally active synthetic progestational hormone used often in combinations as an oral contraceptive.
	Cyproterone - An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
	Danazol - A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
	Dydrogesterone - A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
	Fluocinolone Acetonide - One of the GLUCOCORTICOIDS used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
	Medrogestone - 6,17-Dimethylpregna-4,6-diene-3,20-dione. A synthetic progestational hormone with actions similar to those of progesterone. It is used in the treatment of menstrual irregularities and has also been employed in the treatment of prostatic hypertrophy and endometrial carcinoma.
	Megestrol - 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
	Melengestrol Acetate - A 6-methyl PROGESTERONE acetate with reported glucocorticoid activity and effect on ESTRUS.
	Pregnadienediols - Doubly unsaturated pregnane derivatives with two hydroxy groups substituted anywhere on the rings or side chains.
	Pregnadienetriols - Doubly unsaturated pregnane derivatives substituted with three hydroxy groups anywhere within the ring structure or side chains.
	Triamcinolone - A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)

Pregnadienes Medical Definitions and Terms

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