Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrimidines > Trimethoprim Terms and Definitions
Trimethoprim
| Medical Definition: | A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported. | |
| Guide Notes: | consider TRIMETHOPRIM RESISTANCE for nonsusceptibility of bacteria | |
| Also Called: | Proloprim,Trimpex | |
| CAS Type 1 Name: | CAS Number: | 738-70-5 |
| Previously Indexed: | Anti-Infective Agents (1966-1971),Folic Acid Antagonists (1966-1971),Pyrimidines (1966-1971) |
Trimethoprim Medical Definitions and Terms
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