Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrazines > Amiloride Terms and Definitions

Amiloride

Medical Definition:	A pyrazine compound inhibiting sodium reabsorbtion through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
Also Called:	Amiloride Hydrochloride,Amiloride Hydrochloride, Anhydrous,Midamor
CAS Type 1 Name:	CAS Number:	2609-46-3
Previously Indexed:	Diuretics (1966-1971),Pyrazines (1966-1971)

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com