Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrazines Terms and Definitions




Pyrazines

Medical Definition:
Guide Notes: do not confuse with PYRIDAZINES
Pyrazines Categories.
Canadian Medical Guide Definition Amiloride - A pyrazine compound inhibiting sodium reabsorbtion through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
Canadian Medical Guide Definition Pyrazinamide - A pyrazine that is used therapeutically as an antitubercular agent.

Pyrazines Medical Definitions and Terms

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