Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins Terms and Definitions




Nuclear Proteins

Medical Definition: Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.
Guide Notes: proteins in the cell nucleus: do not confuse with NUCLEOPROTEINS (proteins conjugated with nucleic acids)
Also Called: Nucleolar Proteins,Nuclear Protein
Previously Indexed: Nucleoproteins (1966-1987),Proteins (1966-1987)
Nuclear Proteins Categories.
Canadian Medical Guide Definition Antigens, Nuclear - Immunologically detectable substances found in the CELL NUCLEUS.
Canadian Medical Guide Definition Chromosomal Proteins, Non-Histone - Nucleoproteins which in contrast to histones are acid insoluble. They are involved in chromosomal functions; e.g. they bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens.
Canadian Medical Guide Definition Histones - Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
Canadian Medical Guide Definition Nuclear Matrix-Associated Proteins - A broad category of nuclear proteins that are components of or participate in the formation of the NUCLEAR MATRIX.
Canadian Medical Guide Definition Proliferating Cell Nuclear Antigen - Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.
Canadian Medical Guide Definition Protamines - A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)

Nuclear Proteins Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com





Wildlife On Video »

Canadian Medical Guide Canada's Great Outdoors
Tour Canadian Rockies »
Book Banff »
Book Jasper »
Maligne Lake Boat Cruise »
Gondola Banff »
Hike Jasper »
Jasper Columbia Icefield »