Canadian Medical Guide > Diseases > Musculoskeletal Diseases > Bone Diseases > Bone Diseases, Developmental > Osteochondrodysplasias > Osteogenesis Imperfecta Terms and Definitions
Osteogenesis Imperfecta
Medical Definition: | Autosomal dominant COLLAGEN DISEASES resulting from defective biosynthesis of COLLAGEN TYPE I and characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. There are four major types, I-IV. |
Also Called: | Lobstein's Disease |
Osteogenesis Imperfecta Medical Definitions and Terms
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