Canadian Medical Guide > Diseases > Musculoskeletal Diseases > Bone Diseases > Bone Diseases, Developmental Terms and Definitions

Bone Diseases, Developmental

Medical Definition:
Previously Indexed:	Bone Diseases (1966-1969)

Bone Diseases, Developmental Categories.

	Acro-Osteolysis - A condition with congenital and acquired forms causing recurrent ulcers in the fingers and toes. The congenital form exhibits autosomal dominant inheritance; the acquired form is found in workers who handle VINYL CHLORIDE. When acro-osteolysis is accompanied by generalized OSTEOPOROSIS and skull deformations, it is called HAJDU-CHENEY SYNDROME.
	Dwarfism - The condition of being undersized as a result of premature arrest of skeletal growth. It may be caused by insufficient secretion of growth hormone (DWARFISM, PITUITARY).
	Dysostoses - Defective bone formation involving individual bones, singly or in combination.
	Funnel Chest - A developmental anomaly in which the lower sternum is posteriorly dislocated and concavely deformed, resulting in a funnel-shaped thorax.
	Gigantism - The condition of abnormal overgrowth or excessive size of the whole body or any of its parts.
	Leg Length Inequality - A condition in which one of a pair of legs fails to grow as long as the other, which could result from injury or surgery.
	Marfan Syndrome - A hereditary disorder of connective tissue characterized by tall stature, elongated extremities, subluxation of the lens, dilatation of the ascending aorta, and "pigeon breast." It is inherited as an autosomal dominant trait.
	Osteochondrodysplasias - Abnormal development of cartilage and bone.
	Osteolysis, Essential - Syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. The destruction follows various patterns: massive (Gorham disease), multicentric (HAJDU-CHENEY SYNDROME), or carpal/tarsal.
	Platybasia - A developmental deformity of the occipital bone and upper end of the cervical spine, in which the latter appears to have pushed the floor of the occipital bone upward. (Dorland, 27th ed)

Bone Diseases, Developmental Medical Definitions and Terms

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