Canadian Medical Guide > Chemicals and Drugs > Nucleic Acids, Nucleotides, and Nucleosides > Antisense Elements (Genetics) Terms and Definitions

Antisense Elements (Genetics)

Medical Definition:	Nucleic acids which hybridize to complementary sequences in other target nucleic acids causing the function of the latter to be affected.
Guide Notes:	DF: ANTISENSE ELEMENTS
Also Called:	Antisense Probes

Antisense Elements (Genetics) Categories.

	DNA, Antisense - DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
	Oligonucleotides, Antisense - Short fragments of DNA or RNA that are used to alter the function of target RNAs or DNAs to which they hybridize.
	RNA, Antisense - RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.

Antisense Elements (Genetics) Medical Definitions and Terms

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