Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Nitroso Compounds > Nitrosourea Compounds > Nimustine Terms and Definitions




Nimustine

Medical Definition: Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.
Also Called: NSC 245382
CAS Type 1 Name: CAS Number: 42471-28-3
Previously Indexed: Antineoplastic Agents (1975-1988),Nitrosourea Compounds (1975-1988)

Nimustine Medical Definitions and Terms

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