Canadian Medical Guide > Anatomy > Nervous System > Neurons > Lewy Bodies Terms and Definitions




Lewy Bodies

Medical Definition: Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of injured or fragmented neurons. The presence of Lewy bodies is the histological marker of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may be seen in other neurological conditions. They are typically found in the substantia nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic nuclei, and neocortex.
Guide Notes: LEWY BODY DISEASE is also available
Previously Indexed: Cellular Inclusions (1972-1991),Cytoplasmic Granules (1966-1991)

Lewy Bodies Medical Definitions and Terms

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