Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Complex and Mixed Terms and Definitions

Neoplasms, Complex and Mixed

Medical Definition:	Neoplasms composed of more than one type of neoplastic tissue.
Guide Notes:	neopl composed of more than one type of neopl tissue; indexing policy: Manual section 24; also TN Suppl: Tumor Key for human & corresponding vet tumors (does not contain exper tumors); TN 135: correct use of tissue type terms; /blood supply /chem /second
Previously Indexed:	specific neoplasm (1966-1997)

Neoplasms, Complex and Mixed Categories.

	Adenolymphoma - A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid.
	Adenoma, Pleomorphic - A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
	Adenomyoma - A benign neoplasm of muscle (usually smooth muscle) with glandular elements. It occurs most frequently in the uterus and uterine ligaments. (Stedman, 25th ed)
	Adenosarcoma - A malignant neoplasm arising simultaneously or consecutively in mesodermal tissue and glandular epithelium of the same part. (Stedman, 25th ed)
	Carcinoma, Adenosquamous - A mixed adenocarcinoma and squamous cell or epidermoid carcinoma.
	Carcinosarcoma - A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed)
	Hepatoblastoma - A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
	Mesenchymoma - A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
	Mixed Tumor, Malignant - A malignant tumor composed of more than one type of neoplastic tissue. (Dorland, 27th ed)
	Mixed Tumor, Mesodermal - A sarcoma of the body of the uterus arising in older women, composed of more than one mesenchymal tissue, especially including striated muscle cells. It is associated with previous pelvic radiation exposure in 20% of patients. (Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1702)
	Mixed Tumor, Mullerian - A tumor, basically a carcinoma with a single sarcoma such as leiomyosarcoma or angiosarcoma or multiple sarcomas of uterine origin. The role of estrogen has been postulated as a possible etiological factor in this tumor. (Holland et al., Cancer Medicine, 3d ed, p1703)
	Myoepithelioma - A usually benign tumor made up predominantly of myoepithelial cells.
	Nephroblastoma - A malignant kidney tumor made up of three cell types: blastemal, stromal, and epithelial, but not all present in every case.
	Nephroma, Mesoblastic - A malignant tumor of the kidney characterized by spindled myofibroblastic cells arranged in sheets or bundles with a tendency to infiltrate into the adjoining normal kidney and through the capsule into the perirenal tissues. (From Holland et al., Cancer Medicine, 3d ed, p2208)
	Pulmonary Blastoma - A malignant neoplasm of the lung composed chiefly or entirely of immature undifferentiated cells (i.e., blast forms) with little or virtually no stroma. (From Stedman, 25th ed)
	Rhabdoid Tumor - A rare but highly lethal childhood tumor found almost exclusively in infants. Histopathologically, it resembles RHABDOMYOSARCOMA but the tumor cells are not of myogenic origin. Although it arises primarily in the kidney, it may be found in other parts of the body. The rhabdoid cytomorphology is believed to be the expression of a very primitive malignant cell. (From Holland et al., Cancer Medicine, 3d ed, p2210)
	Sarcoma, Endometrial Stromal - A highly malignant subset of neoplasms arising from the endometrial stroma. Tumors in this group infiltrate the stroma with a wide range of atypia cells and numerous mitoses. They are capable of widespread metastases (NEOPLASM METASTASIS).
	Thymoma - A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant and probably not neoplastic. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (Stedman, 25th ed)

Neoplasms, Complex and Mixed Medical Definitions and Terms

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