Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Leukemia Terms and Definitions

Leukemia

Medical Definition:	A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. It is classified according to degree of cell differentiation as acute or chronic, and according to predominant type of cell involved as myelogenous or lymphocytic. (Dorland, 28th ed)
Guide Notes:	note all the leukemia terms & cross-refs for the many types of leukemia; if not here, check Tumor Manual or Tumor Key; do not use /blood supply /chem /second /secret /ultrastruct; radiation-induced = LEUKEMIA, RADIATION-INDUCED; leukemic infiltration = LE

Leukemia Categories.

	Leukemia, Experimental - Leukemia induced experimentally by administration of various leukemogenic agents, viruses, radiation or transplantation.
	Leukemia, Hairy Cell - A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
	Leukemia, Lymphocytic - Leukemia associated with hyperplasia and overactivity of the lymphoid tissue. There are increased numbers of circulating malignant lymphocytes and lymphoblasts. (Dorland, 28th ed, p919)
	Leukemia, Mast-Cell - A form of systemic mastocytosis (MASTOCYTOSIS, SYSTEMIC) characterized by the presence of large numbers of tissue MAST CELLS in the peripheral blood without skin lesions. It is a high-grade LEUKEMIA disease with bone marrow smear of >20% MAST CELLS, multi-organ failure and a short survival.
	Leukemia, Myeloid - Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors in the bone marrow and other sites.
	Leukemia, Plasmacytic
	Leukemia, Radiation-Induced
	Leukemia, Subleukemic - A form of leukemia that occurs without elevated levels of leukocytes within the blood. Lesions containing abnormal leukocytes can be found within tissues.

Leukemia Medical Definitions and Terms

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