Canadian Medical Guide > Diseases > Cardiovascular Diseases > Heart Diseases > Myocardial Diseases > Myocardial Reperfusion Injury Terms and Definitions




Myocardial Reperfusion Injury

Medical Definition: Functional, metabolic, or structural changes in ischemic heart muscle thought to result from REPERFUSION to the ischemic areas. Changes can be fatal to muscle cells and may include edema with explosive cell swelling and disintegration, sarcolemma disruption, fragmentation of mitochondria, contraction band necrosis, enzyme washout, and calcium overload. Other damage may include hemorrhage and ventricular arrhythmias. One possible mechanism of damage is thought to be oxygen free radicals. Treatment currently includes the introduction of scavengers of oxygen free radicals, and injury is thought to be prevented by warm blood cardioplegic infusion prior to reperfusion.
Previously Indexed: Coronary Circulation (1975-1988),Coronary Disease (1971-1988),Ischemia (1971-1988),Myocardial Infarction (1973-1988),Perfusion (1971-1988)

Myocardial Reperfusion Injury Medical Definitions and Terms

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com





Wildlife On Video »

Canadian Medical Guide Canada's Great Outdoors
Tour Canadian Rockies »
Book Banff »
Book Jasper »
Maligne Lake Boat Cruise »
Gondola Banff »
Hike Jasper »
Jasper Columbia Icefield »