Canadian Medical Guide > Biological Sciences > Genetic Processes > Mutagenesis > Gene Duplication Terms and Definitions

Gene Duplication

Medical Definition:	Processes occurring in various organisms by which new genes arise, i.e. the duplication of a single gene. In contiguous gene duplication, the duplicated sequence coexists within the boundaries set by the start and stop signals for protein synthesis of the original, resulting in a larger transcription product and protein at the expense of the prexisting protein. In discrete gene duplication, the duplicated sequence is outside the start and stop signals, resulting in two independent genes (GENES, DUPLICATE) and gene products. Gene duplication may result in a MULTIGENE FAMILY; supergenes or PSEUDOGENES. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Guide Notes:	do not confuse with GENES, DUPLICATE
Previously Indexed:	Multigene Family (1987-1998)

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