Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Lactones > Macrolides > Sirolimus Terms and Definitions
Sirolimus
| Medical Definition: | A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. |
| Also Called: | AY 22-989,Rapamune |
| CAS Number: | 53123-88-9 |
| Previously Indexed: | Polyenes (1976-1998) |
Sirolimus Medical Definitions and Terms
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