Canadian Medical Guide > Diseases > Neoplasms > Neoplasms by Histologic Type > Lymphoma > Immunoproliferative Small Intestinal Disease Terms and Definitions

Immunoproliferative Small Intestinal Disease

Medical Definition:	A condition that is caused by HYPERPLASIA of LYMPHOCYTES in the small intestine (INTESTINE, SMALL) and the mesenteric LYMPH NODES. These lymphocytes produce an anomalous heavy chain protein. Generally, these IPSID patients have either concurrent LYMPHOMA or develop lymphoma within a few years. The disease was originally described in the Mediterranean region.
Also Called:	Lymphoma, Mediterranean
Previously Indexed:	Heavy Chain Disease (1966-1986),Intestinal Neoplasms (1966-1986),Lymphoma (1966-1986)

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