Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Amides > Lactams > Cephalosporins Terms and Definitions
Cephalosporins
Medical Definition: | A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid. |
Also Called: | Cephalosporanic Acids |
Cefamandole - Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate. | |
Cefazolin - A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine. | |
Cefonicid - A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections. | |
Cefsulodin - A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for Pseudomonas infections in debilitated patients. | |
Cephacetrile - A derivative of 7-aminocephalosporanic acid. | |
Cephalexin - A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms. | |
Cephaloridine - A cephalosporin antibiotic. | |
Cephamycins - Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms. |
Cephalosporins Medical Definitions and Terms
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