Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Amides > Lactams > Carbapenems Terms and Definitions
Carbapenems
Medical Definition: | A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain. |
Previously Indexed: | Antibiotics (1966-1982),Antibiotics, Lactam (1983-1989) |
Thienamycins - Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors. |
Carbapenems Medical Definitions and Terms
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