Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Heterocyclic Compounds, 2-Ring > Indoles > Cytochalasins Terms and Definitions
Cytochalasins
Medical Definition: | A group of fungal metabolites that affect the motility of polymorphonuclear leukocytes. |
Guide Notes: | /antag permitted but consider also ANTITOXINS;/biosyn permitted if by fungus |
Previously Indexed: | Indoles (1966-1972),specific fungus (1966-1972) |
Cytochalasin B | |
Cytochalasin D - A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release. |
Cytochalasins Medical Definitions and Terms
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