Canadian Medical Guide > Analytical, Diagnostic and Therapeutic Techniques and Equipment > Diagnosis > Laboratory Techniques and Procedures > Hematologic Tests > Blood Coagulation Tests Terms and Definitions

Blood Coagulation Tests

Medical Definition:	Laboratory tests for evaluating the individual's clotting mechanism.
Guide Notes:	GEN: prefer specifics; NIM; coord with disease /blood, not /physiopathol; DF: BLOOD COAG TESTS

Blood Coagulation Tests Categories.

	International Normalized Ratio - System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.
	Partial Thromboplastin Time - The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.
	Prothrombin Time - Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. Factors measured are FIBRINOGEN; PROTHROMBIN; FACTOR V; FACTOR VII; and FACTOR X. It is used for monitoring anticoagulant therapy with COUMARINS.
	Thrombelastography - Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.
	Thrombin Time - Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.
	Whole Blood Coagulation Time - The time required by whole blood to produce a visible clot.

Blood Coagulation Tests Medical Definitions and Terms

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