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Chimerin Proteins - A family of GTPASE-ACTIVATING PROTEINS that are specific for RAC GTP-BINDING PROTEINS. |
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Eukaryotic Initiation Factor-5 - A eukayotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP causes the release of EUKARYOTIC INITIATION FACTOR-2 and EUKARYOTIC INITIATION FACTOR-3 from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex |
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ras GTPase-Activating Proteins - PROTEINS that specifically activate the GTP-phosphohydrolase activity of RAS PROTEINS. |
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RGS Proteins - A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it to revert to its inactive (GDP-bound) form. |