Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Telomere-Binding Proteins Terms and Definitions

Telomere-Binding Proteins

Medical Definition:	Proteins that specifically bind to TELOMERES. Proteins in this class include those that perform functions such as telomere capping, telomere maintenance and telomere stabilization.
Guide Notes:	coordinate with MITOCHONDRIAL PROTEINS (IM) if from MITOCHONDRIA; see SCR for specific terms
Also Called:	Double-Stranded Telomere-Binding Proteins,Mitochondrial Telomere-Binding Proteins,Single-Stranded Telomere-Binding Proteins,Telomer-Binding Protein, alpha-Subunit,Telomer-Binding Protein, beta-Subunit,Telomere Repeat Binding Proteins
Previously Indexed:	DNA-Binding Proteins (1991-2002)

Telomere-Binding Proteins Categories.

	Telomeric Repeat Binding Protein 1 - A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELEMORIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.
	Telomeric Repeat Binding Protein 2 - A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the cell cycle. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 1 in that it contains basic N-terminal amino acid residues.

Telomere-Binding Proteins Medical Definitions and Terms

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