Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Proto-Oncogene Proteins c-rel Terms and Definitions
Proto-Oncogene Proteins c-rel
| Medical Definition: | Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis. |
| Previously Indexed: | Proto-Oncogene Proteins (1988-1999) |
Proto-Oncogene Proteins c-rel Medical Definitions and Terms
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