Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Proto-Oncogene Proteins c-jun Terms and Definitions




Proto-Oncogene Proteins c-jun

Medical Definition: Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.
Guide Notes: /drug eff /ultrastruct permitted; DF: note short X refs
Also Called: jun B Proteins,jun D Proteins
Previously Indexed: DNA-Binding Proteins (1987-1991),Proto-Oncogene Proteins (1987-1991),Transcription Factors (1987-1991)

Proto-Oncogene Proteins c-jun Medical Definitions and Terms

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