Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Proto-Oncogene Proteins c-fos Terms and Definitions

Proto-Oncogene Proteins c-fos

Medical Definition:	Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.
Guide Notes:	/drug eff /ultrastruct permitted; not for c-fos 39 ( = C-FOS-ASSOCIATED PROTEINS P39 see PROTO-ONCOGENE PROTEINS C-JUN); DF: note short X refs
Also Called:	Fos B Protein,Antigens, Fos-Related
Previously Indexed:	Proto-Oncogene Proteins (1985-1991)

CANADIAN MEDICAL GUIDE

Thank you for visiting Canadian Medical Guide .com