Canadian Medical Guide > Chemicals and Drugs > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > I-kappa B Terms and Definitions

I-kappa B

Medical Definition:	Family of inhibitory proteins which bind to the rel family of transcription factors and modulate their activity. The transcription factor NF-KAPPA B is generally present in an inactive cytoplasmic form, bound to inhibitory IkB proteins. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
Previously Indexed:	DNA-Binding Proteins (1998-1999),Proto-Oncogene Proteins (1993-1998)

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