Canadian Medical Guide > Chemicals and Drugs > Neurotransmitters and Neurotransmitter Agents > Neurotransmitter Agents > Cholinergic Agents > Cholinesterase Inhibitors Terms and Definitions

Cholinesterase Inhibitors

Medical Definition:	Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Guide Notes:	DF: CHOLINESTERASE INHIB
Also Called:	Acetylcholinesterase Inhibitors,Cholinesterase Inhibitors, Irreversible,Cholinesterase Inhibitors, Reversible

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