Canadian Medical Guide > Chemicals and Drugs > Anti-Inflammatory Agents, Antirheumatic Agents, and Inflammation Mediators > Inflammation Mediators > Chemokines > Macrophage Inflammatory Proteins Terms and Definitions




Macrophage Inflammatory Proteins

Medical Definition: Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of macrophages, these chemokines are produced by a variety of cell types including neutrophils, fibroblasts, and epithelial cells. They likely play a significant role in respiratory tract defenses.
Guide Notes: heparin-binding proteins; DF: MACROPHAGE INFLAMM PROTEINS
Macrophage Inflammatory Proteins Categories.
Canadian Medical Guide Definition Macrophage Inflammatory Protein-1 - A chemokine that is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating hematopoiesis. Its two variants, MIP-1alpha and MIP-1beta, are 60% homologous to each other.

Macrophage Inflammatory Proteins Medical Definitions and Terms

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