Canadian Medical Guide > Chemicals and Drugs > Anti-Inflammatory Agents, Antirheumatic Agents, and Inflammation Mediators > Inflammation Mediators Terms and Definitions

Inflammation Mediators

Medical Definition:	The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).
Guide Notes:	endogenous & exogenous mediators; do not confuse with ANTI-INFLAMMATORY AGENTS which are exogenous & counteract or treat inflamm; DF: INFLAMM MEDIATORS

Inflammation Mediators Categories.

	Autacoids - A chemically diverse group of substances produced by various tissues in the body that cause slow contraction of smooth muscle; they have other intense but varied pharmacologic activities.
	Chemokines - Class of pro-inflammatory cytokines that have the ability to attract and activate leukocytes. They can be divided into at least three structural branches: C; (CHEMOKINES, C); CC; (CHEMOKINES, CC); and CXC; (CHEMOKINES, CXC); according to variations in a shared cysteine motif.

Inflammation Mediators Medical Definitions and Terms

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