Canadian Medical Guide > Diseases > Musculoskeletal Diseases > Joint Diseases > Arthritis > Arthritis, Rheumatoid Terms and Definitions




Arthritis, Rheumatoid

Medical Definition: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
Guide Notes: in children = ARTHRITIS, JUVENILE RHEUMATOID; includes PCE: polyarthrite chronique évolutive; tends to be chronic so do not coord with CHRONIC DISEASE
Arthritis, Rheumatoid Categories.
Canadian Medical Guide Definition Arthritis, Juvenile Rheumatoid - Rheumatoid arthritis of children occurring in three major subtypes defined by the symptoms present during the first six months following onset: systemic-onset (Still's Disease, Juvenile-Onset) polyarticular-onset, and pauciarticular-onset. Adult-onset cases of Still's disease (STILL'S DISEASE, ADULT-ONSET) are also known. Only one subtype of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.
Canadian Medical Guide Definition Caplan's Syndrome - Pneumoconiosis associated with rheumatoid arthritis.
Canadian Medical Guide Definition Felty's Syndrome - A combination of rheumatoid arthritis, splenomegaly, leukopenia, pigmented spots on lower extremities, and other evidence of hypersplenism (anemia and thrombocytopenia). (From Dorland, 27th ed)
Canadian Medical Guide Definition Rheumatoid Nodule - Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.
Canadian Medical Guide Definition Sjogren's Syndrome - Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
Canadian Medical Guide Definition Still's Disease, Adult-Onset - Systemic-onset rheumatoid arthritis in adults. It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalized lymphadenopathy and hepatosplenomegaly are more prominent.

Arthritis, Rheumatoid Medical Definitions and Terms

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