Canadian Medical Guide > Chemicals and Drugs > Central Nervous System Agents > Psychotropic Drugs > Antidepressive Agents > Antidepressive Agents, Tricyclic Terms and Definitions
Antidepressive Agents, Tricyclic
| Medical Definition: | Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. |
| Guide Notes: | GEN or unspecified; prefer specifics |
| Previously Indexed: | Antidepressive Agents (1968-1974) |
Antidepressive Agents, Tricyclic Medical Definitions and Terms
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