Canadian Medical Guide > Diseases > Endocrine Diseases > Adrenal Gland Diseases > Adrenal Gland Hypofunction > Addison's Disease Terms and Definitions

Addison's Disease

Medical Definition:	A disease characterized by hypotension, weight loss, anorexia, weakness, and sometimes a bronze-like melanotic hyperpigmentation of the skin. It is due to tuberculosis- or autoimmune-induced disease (hypofunction) of the adrenal glands that results in deficiency of aldosterone and cortisol. In the absence of replacement therapy, it is usually fatal.
Guide Notes:	an autoimmune dis with adrenal hypofunction

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