Canadian Medical Guide > Diseases > Endocrine Diseases > Adrenal Gland Diseases > Adrenal Gland Hypofunction Terms and Definitions




Adrenal Gland Hypofunction

Medical Definition: Adrenocortical hypofunction includes all conditions in which adrenal steroid hormone secretion falls below the requirements of the body. Adrenal insufficiency may be divided into two general categories: (1) those associated with primary inability of the adrenal to elaborate sufficient quantities of hormone and (2) those associated with a secondary failure due to a primary failure in the elaboration of adrenocorticotropin. (Harrison's Principles of Internal Medicine, 13th ed, p1970)
Guide Notes: do not confuse with ADRENAL GLAND HYPERFUNCTION
Adrenal Gland Hypofunction Categories.
Canadian Medical Guide Definition Addison's Disease - A disease characterized by hypotension, weight loss, anorexia, weakness, and sometimes a bronze-like melanotic hyperpigmentation of the skin. It is due to tuberculosis- or autoimmune-induced disease (hypofunction) of the adrenal glands that results in deficiency of aldosterone and cortisol. In the absence of replacement therapy, it is usually fatal.
Canadian Medical Guide Definition Hypoaldosteronism - Aldosterone deficiency, usually associated with hypoadrenalism, and characterized by hypotension, dehydration, and a tendency to excrete excessive amounts of sodium. A selective aldosterone deficiency resulting from low renin production is called hyporeninemic hypoaldosteronism. (From Dorland, 28th ed; Stedman, 26th ed)

Adrenal Gland Hypofunction Medical Definitions and Terms

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