Canadian Medical Guide > Chemicals and Drugs > Heterocyclic Compounds > Acids, Heterocyclic > Nicotinic Acids Terms and Definitions

Nicotinic Acids

Medical Definition:	2-, 3-, or 4-Pyridinecarboxylic acids. Pyridine derivatives substituted with a carboxy group at the 2-, 3-, or 4-position. The 3-carboxy derivative (NIACIN) is active as a vitamin.
Guide Notes:	B vitamins; /biosyn /physiol permitted; /defic = PELLAGRA; /ther use: coord disease with /drug ther, not /diet ther

Nicotinic Acids Categories.

	Arecoline - An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetycholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
	Clonixin - Anti-inflammatory analgesic.
	Etazolate - A potent phosphodiesterase inhibitor proposed as an antipsychotic agent.
	Niacin - A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
	Niacinamide - An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
	Niceritrol - An ester of nicotinic acid that lowers cholesterol and triglycerides in total plasma and in the VLD- and LD-lipoprotein fractions.
	Niflumic Acid - An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
	Pipemidic Acid - Antimicrobial against Gram negative and some Gram positive bacteria. It is protein bound and concentrated in bile and urine and used for gastrointestinal, biliary, and urinary infections.
	Piromidic Acid - Antibacterial against mainly gram negative organisms. It is used for urinary tract and intestinal infections.
	Xanthinol Niacinate - A vasodilator used in peripheral vascular disorders and insufficiency. It may cause gastric discomfort and hypotension.

Nicotinic Acids Medical Definitions and Terms

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